African champions Nigeria need only a point to win the group while The Flames must win the tie to finish top.
Nigeria coach Stephen Keshi is hoping off the field controversies will not affect his team
While Belgian coach Tom Saintfiet has taken charge of Malawi with the sole purpose of beating Nigeria and helping the Flames qualify for Brazil.
Santifiet is working with the team for free and has given up any potential win bonus.
Meanwhile, Kenya host Namibia in the other game in this group where a win for the Harambee Stars would see them avoid finishing bottom of the group.