A lorry registration number LA 8910 has been gutted down by fire along Masasa-Golomoti road (Khwekhwelere) in Dedza district.
The incident happened on Thursday night, according to the law enforcers.
All passengers have escaped unhurt.
The vehicle was loaded with bags of charcoal and ascending the hills from Golomoti side heading to Dedza boma.
The cause of the fire is not yet known at the moment.